William J Hurst Selected Research

tetrahydro-pyran-4-carboxylic acid (2- methyl- 4- (2- methyl- (1,3')bipyrrolidinyl- 1'- yl)phenyl)amide

11/2013

Discovery of a potent, selective, and orally bioavailable histamine H3 receptor antagonist SAR110068 for the treatment of sleep-wake disorders.

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William J Hurst Research Topics

Disease

2	Obesity 06/2013 - 06/2013
1	Alzheimer Disease (Alzheimer's Disease) 01/2014
1	Disease Progression 01/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014
1	Sleep Wake Disorders 11/2013
1	Body Weight (Weight, Body) 05/2011
1	Wounds and Injuries (Trauma) 01/2006
1	Synostosis 09/2004

Drug/Important Bio-Agent (IBA)

2	AmidesIBA 06/2013 - 06/2013
2	Histamine H3 AntagonistsIBA 06/2013 - 06/2013
1	Peptides (Polypeptides)IBA 01/2014
1	tau Proteins (tau Protein)IBA 01/2014
1	Amyloid (Amyloid Fibrils)IBA 01/2014
1	Histamine H3 Receptors (Histamine H3 Receptor)IBA 11/2013
1	tetrahydro-pyran-4-carboxylic acid (2- methyl- 4- (2- methyl- (1,3')bipyrrolidinyl- 1'- yl)phenyl)amideIBA 11/2013
1	PolyphenolsIBA 05/2011
1	EnzymesIBA 05/2011

Therapy/Procedure

2	Sutures (Suture) 01/2006 - 09/2004
1	Therapeutics 01/2014
1	Caloric Restriction 05/2011